Infection Probability Calculator - Neonatal Sepsis Calculator

Kaiser Permanente Neonatal Early-Onset Sepsis

Neonatal Early-Onset Sepsis Calculator (2024 Update)

Probability of Neonatal Early-Onset Sepsis Based on Maternal Risk Factors and the Infant's Clinical Presentation

The tool below is intended for the use of clinicians trained and experienced in the care of newborn infants. Using this tool, the risk of early-onset sepsis can be calculated in an infant born > 35 weeks gestation. The interactive calculator produces the probability of early onset sepsis per 1000 babies by entering values for the specified maternal risk factors along with the infant's clinical presentation.

Please enter details below.

Predictor	Scenario
Calculator Version	Original (2017) - No Universal GBS Screening Updated (2024) - Universal GBS Screening
Incidence of Early-Onset Sepsis
Gestational age	weeks days
Highest maternal antepartum temperature
ROM (Hours)
Maternal GBS status	Negative Positive Unknown
Type of intrapartum antibiotics	Broad spectrum antibiotics > 4 hrs prior to birth Broad spectrum antibiotics 2-3.9 hrs prior to birth GBS specific antibiotics > 2 hrs prior to birth No antibiotics or any antibiotics < 2 hrs prior to birth

Risk per 1000/births
EOS Risk @ Birth

EOS Risk after Clinical Exam	Risk per 1000/ births	Clinical Recommendation	Vitals
Well Appearing
Equivocal
Clinical Illness

EOS Risk after Clinical Exam	Risk per 1000/births
Well Appearing
Equivocal
Clinical Illness

EOS Risk after Clinical Exam	Clinical Recommendation
Well Appearing
Equivocal
Clinical Illness

EOS Risk after Clinical Exam	Vitals
Well Appearing
Equivocal
Clinical Illness

Classification of Infant's Clinical Presentation Clinical Illness Equivocal Well Appearing

Original EOS Calculator 2017 version

Contact us! Send your e-mail at PerinatalResearchUnit@kp.org